Non-Mammalian cDNA
Non-Mammalian cDNA
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Cayman Chemical LPA2 ntagonIst 1 5mg
A fluorescent affinity probe for amyloid-B with ex /em spectra of 498/578 nm respectively binds to AB40 monomers and aggregates as well as AB42 monomers dimers and oligomers (Kds 68 8 52 4 159 7 162 9 and 85 7 nM respectively) fluorescence decreases when bound labels amyloid plaques and cerebral amyloid angiopathy both in APP/PS1 mouse brain sections and in live mice following i v administration inhibits copper-induced and naturally occurring AB crosslinking
