Magnetic Affinity Separation Particles
Enzo Life Sciences DEEPSEE CDKN2A/CEN3/7/17 Quad Probe Assay (20tests)
DEEPSEE CDKN2A/CEN3/7/17 Quad Probe Assay contains fluorescently labeled nucleic acid probes for use in in situ hybridization to detect the most frequently encountered chromosomal abnormalities in bladder cancer cells. This includes three chromosome enumeration probes targeted to specific alpha satellite regions within the centromeres of chromosomes 3, 7, and 17. These probes, namely CEN 3 (red), CEN 7 (green), and CEN 17 (aqua), allow for rapid determination of chromosomal aneuploidy that is commonly found in bladder cancer cells. The fourth probe, CDKN2A (gold), targets the 9p21 locus enabling the detection of deletions or alterations of the tumor suppressor gene CDKN2A, also known as p16 or p16INK4a. Loss of this tumor suppressor gene often occurs in a wide variety of human tumors including bladder carcinoma. Alternative name: CDKN2A/CEN3/7/17 Quadruple Probe. Applications: Fluorescent detection FISH.
