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Tocris Bioscience™ ITD 1
Selective inhibitor of TGF-β signaling; induces cardiomyocyte differentiation in ESCs
Supplier: Tocris Bioscience™ 5068/10
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Description
ITD 1 is a selective inhibitor of TGF-β signaling (IC50 = 0.85 μM); displays little or no inhibition of activin, Wnt or BMP signaling pathways. Induces proteasomal degradation of the TGF-β type II receptor. Inhibits TGF-β-induced mesoderm formation from mouse embryonic stem cells (ESCs) during early differentiation; selectively promotes the differentiation of ESCs to cardiomyocytes in vitro between days 3-5. Does not induce differentiation of vascular smooth muscle cells or endothelial cells.Specifications
| >98% | |
| 10 mg | |
| 415.52 |
| -20°C | |
| ITD 1 | |
| ITD 1 |
Product Title
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