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Tocris Bioscience™ L-755,507
Very potent and selective β3 partial agonist
Supplier: Tocris Bioscience™ 2197/50
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Description
L-755,507 is a potent β3-adrenergic receptor partial agonist > 1000-fold selective over β1- and β2-adrenoceptors (EC50 values are 0.43, 580 and > 10000 nM for activation of cloned human β3-, β1- and β2-adrenoceptors respectively). Stimulates lipolysis in rhesus adipocytes in vitro (EC50 = 3.9 nM). Enhances CRISPR-mediated homology-directed repair (HDR) efficiency 2-3-fold for large fragments and ∽9-fold for point mutations, in human induced pluripotent stem cells (iPSCs).Specifications
| >98% | |
| L-755,507 | |
| L-755,507 |
| 50 mg | |
| 584.73 |
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