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Tocris Bioscience™ L-755,507
Very potent and selective β3 partial agonist
$279.00 - $1165.00
Specifications
| Purity | >98% |
|---|---|
| Product Type | L-755,507 |
| Molecular Weight (g/mol) | 584.73 |
| Inhibitors | L-755,507 |
Description
Potent β3-adrenergic receptor partial agonist > 1000-fold selective over β1- and β2-adrenoceptors (EC50 values are 0.43, 580 and > 10000 nM for activation of cloned human β3-, β1- and β2-adrenoceptors respectively). Stimulates lipolysis in rhesus adipocytes in vitro (EC50 = 3.9 nM). Enhances CRISPR-mediated homology-directed repair (HDR) efficiency 2-3-fold for large fragments and ∽9-fold for point mutations, in human induced pluripotent stem cells (iPSCs).This product(s) resides on a Fisher Scientific GSA or VA contract. If you are viewing this page as a nonregistered user, the price(s) displayed is List Price. To view your GSA or VA contract pricing, log in using your account number, or become a registered user by contacting one of our Customer Service teams. You can also view your contract price by searching for this item(s) on GSA Advantage. To place an order, contact Fisher Scientific Customer Service.
Specifications
| >98% | |
| L-755,507 | |
| 584.73 | |
| L-755,507 |
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