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Tocris Bioscience™ NPS 2143 hydrochloride

Selective calcium-sensing receptor (CaSR) antagonist; orally active calcilytic agent

Supplier: Tocris Bioscience™ 3626/10

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Catalog No. 36-261-0R

$324.50 / Each of 1

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Description

NPS 2143 hydrochloride is a selective Ca2+-sensing receptor antagonist. Blocks increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells (IC50 = 43 nM). Also stimulates parathyroid hormone secretion from bovine parathyroid cells (EC50 = 41 nM). Orally active calcilytic compound.

Specifications

Purity	>99%
Product Type	NPS 2143 hydrochloride
Inhibitors	NPS 2143 hydrochloride

Quantity	10 mg
Molecular Weight (g/mol)	445.38

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Tocris Bioscience™ NPS 2143 hydrochloride

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