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Tocris Bioscience™ NPS 2143 hydrochloride
Selective calcium-sensing receptor (CaSR) antagonist; orally active calcilytic agent
Supplier: Tocris Bioscience™ 3626/50
Description
NPS 2143 hydrochloride is a selective Ca2+-sensing receptor antagonist. Blocks increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells (IC50 = 43 nM). Also stimulates parathyroid hormone secretion from bovine parathyroid cells (EC50 = 41 nM). Orally active calcilytic compound.Specifications
>99% | |
NPS 2143 hydrochloride | |
NPS 2143 hydrochloride |
50 mg | |
445.38 |
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