Cell Lines and Blood Products
Cell Lines and Blood Products
MilliporeSigma™ N27 Rat Dopaminergic Neural Cell Line
characterized in studies of dopamine biosynthesis, neurotoxicity and used as a dopaminergic neuron model for in vitro and in vivo studies.
ENZO LIFE SCIENCES DOPAMINE-B-HYDROXYLASE POLYCLO
NC3311539 DOPAMINE-B-HYDROXYLASE POLYCLO
Sigma Aldrich Fine Chemicals Biosciences DOPAMINE-1 1 2 2-D4 HYDROCHL5G
Dopamine-1,1,2,2-d4 hydrochloride, 5g, 203633-19-6
Eurofins Discoverx ChemiScreen D1 Dopamine Receptor Membrane Preparation, 1 vial. (HTS102M)
The ChemiScreen D1 Dopamine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of DRD1 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx ChemiScreen D3 Dopamine Receptor Membrane Preparation, 1 vial. (HTS103M)
The ChemiScreen D3 Dopamine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of DRD3 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx ChemiScreen D5 Dopamine Receptor Membrane Preparation, 1 vial. (HTS129M)
The ChemiScreen D5 Dopamine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of DRD5 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx ChemiScreen D2 Dopamine Receptor Membrane Preparation, 1 vial. (HTS039M)
The ChemiScreen D2 Dopamine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of DRD2 surface expression. ChemiScreen membrane preps can be used to screen for GPCR activity using GTPγS assays. Increased GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx ChemiScreen D1 Dopamine Receptor Stable Cell Line, 2 vials. (HTS102C)
The ChemiScreen D1 Dopamine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of DRD1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses DRD1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of DRD1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen D4 Dopamine Receptor Stable Cell Line, 2 vials. (HTS223C)
The ChemiScreen D4 Dopamine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of DRD4 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses DRD4 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of DRD4, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen D2 Dopamine Receptor Stable Cell Line, 2 vials. (HTS039C)
The ChemiScreen D2 Dopamine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of DRD2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses DRD2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of DRD2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen D2L Dopamine Receptor Stable Cell Line, 2 vials. (HTS039C2)
The ChemiScreen D2L Dopamine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of DRD2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses DRD2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of DRD2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen D5 Dopamine Receptor Stable Cell Line, 2 vials. (HTS129C)
The ChemiScreen D5 Dopamine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of DRD5 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses DRD5 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of DRD5, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay D1 Dopamine Receptor Frozen Cells, 2 Vials of Cells. (HTS102RTA)
The Ready-to-Assay D1 Dopamine Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. dopamine) based activation of DRD1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses DRD1 alongside exogenous levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of DRD1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx Ready-to-Assay D2L Dopamine Receptor Frozen Cells, 2 Vials of Cells. (HTS039RTA)
The Ready-to-Assay D2L Dopamine Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. dopamine) based activation of DRD2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses DRD2 alongside exogenous levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of DRD2, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.