Custom Peptides
Custom Peptides
Genscript Corporation OVA Peptide (257-264)
This is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
Cayman Chemical MTSETchlorIde 10mg
A reversible inhibitor of both agonist and antagonist binding to diverse GPCRs blocks the binding of radiolabeled ligands to human opioid adrenergic muscarinic dopaminergic adenosine and purinergic receptors with IC50 values of 0 1 to 1 8 UM
Cayman Chemical Muricholic ACD 10mg
An adenosine A3 receptor antagonist binds to the human adenosine A3 receptor (Ki 0 0189 UM) as well as selectively binds rat adenosine A3 over A1 and A2A receptors (Kis 0 113 15 6 and 2 05 UM respectively) in radioligand binding assays inhibits the proliferation of B16-BL6 mouse melanoma cells at 1 UM
Cayman Chemical 1 2DIlInoleoylsnglycero3 10mg
An orally available selective VEGFR inhibitor (IC50s 0 21 0 16 and 0 24 nM for VEGFR1 VEGFR2 and VEGFR3 respectively) also inhibits c-Kit and PDGFRB (IC50s 1 63 and 1 72 nM respectively)
Cayman Chemical MRT67307hydrochlorIde 10mg
A PKA activator (Ka 0 05 UM) selective for PKA over PKG (Ka 5 8 UM) more resistant to hydrolysis by PDEs than cAMP inhibits the proliferation of HL-60 cells (IC50 18 UM after six days) induces relaxation of phenylephrine-precontracted isolated rabbit carotid or renal arterial rings at 10-300 UM intradermal administration prevents SLIGRL-NH2-induced scratching and increases in cutaneous LTB4 production in mice at 10 nmol/site
Cayman Chemical 3 4-DIchloroIsocoumarIn 10mg
An inhibitor of hGIIA sPLA2 (IC50 9 nM) as well as mouse GIIA (mGIIA) hGIIE mGIIE hGX and mGX PLA2s but poorly inhibits other PLA2 enzymes inhibits serum sPLA2 activity in transgenic mice expressing human sPLA2 when given either intravenously or orally
Cayman Chemical GemIfloxacInmesylate 10mg
A broad-spectrum tetracycline antibiotic that inhibits protein synthesis in both Gram-positive and Gram-negative bacteria
Cayman Chemical ChLRzoxazon NGlucuronIde 10mg
A dimeric spiroisoxazoline derived from marine sponges that inhibits proliferation of HeLa cells with an IC50 value of 29 UM
Cayman Chemical Fructose1 6bIsphosphatse1 10mg
A chemiluminescent probe for superoxide production by activated leukocytes
Cayman Chemical SomatostatIn-14humnmouse 10mg
A sesquiterpene alcohol found in patchouli oil that has antibacterial antifungal and antiviral actions suppresses inflammation induced by lipopolysaccharide in vivo accelerates recovery from UV irradiation-induced skin damage through antioxidant and anti-inflammatory effects
Cayman Chemical C18 CeramIded18 118 0 10mg
A histamine H1 receptor antagonist (Ki 10 nM) reverses acetyl-b-methylcholine-induced contraction of isolated rat tracheal strips inhibits expression of IL-8 in TNF-a-stimulated HCT116 and COLO 205 cells reduces severity of colitis and phospho-IKB kinase activation in a mouse model of DSS-induced colitis
Cayman Chemical 4-MethylumbelIferylD-N N 10mg
A homolog of vitamin K2 formed primarily via conversion of vitamin K1 in vivo halts the cell cycle at the G1 phase in HepG2 Hep3B and Huh7 hepatocellular carcinoma cells in a concentration-dependent manner inhibits IKB IKBa phosphorylation and the transcriptional activity of NF-KB
Cayman Chemical W-MurIcholIc AcId 10mg
A potent agonist of GPR119 (EC50s 2 7 and 33 nM for human and rat forms respectively) significantly reduces blood glucose and glycated hemoglobin levels in Zucker diabetic fatty rats
Cayman Chemical NorverapamIlhydrochlorIde 10mg
Inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397 decreases cell viability of T47D breast cancer and C8161 melanoma cell lines at 100 UM