Toxins
Toxins
Sigma Aldrich Fine Chemicals Biosciences Pertussis toxin from Borde2MG
Pertussis toxin from Borde2MG
Toxin Technologies Inc HIGHLY PURIFIED SEB 1MG
SEB; Highly Purified; 1mg; Intended for laboratory and research purposes only; Not intended for human or veterinary drug use
List Biological Laboratories Inc Cholera Toxin (AZIDE-FREE) from Vibrio cholerae, 1 mg
Since 1978, List Labs products are unsurpassed in quality, consistency, and reliability for the success of your research and development project! Cholera toxin is an oligomeric protein of MW 84,000 daltons which consists of a single A subunit surrounded by five B subunits. It is a potent activator of adenylate cyclase and is the pathogenic agent responsible for the symptoms of cholera. Cholera toxin has become a powerful research tool not only in microbiology, but in the fields of physiology, cell biology and biochemistry, as well. Because of the effect on adenylate cyclase, cholera toxin is frequently used for the study of signal transduction mechanisms. In addition, cholera toxin acts as an adjuvant through the stimulation of B-lymphocytes. Cholera toxin is isolated from Vibrio cholerae type Inaba 569B and purified from endotoxin.
Sigma Aldrich Fine Chemicals Biosciences Cholera Toxin from Vibrio cholerae, 9012-63-9, MFCD00130776, 0.5 mg
Synonym: CTX, Cholera enterotoxin, Cholergen, ~95% (SDS-PAGE), lyophilized powder. Cholera Toxin from Vibrio cholerae has been used as a positive control in cAMP (cyclic AMP) assay for enterotoxins. It has been added as a supplement in cell culture media of primary tumors and epithelial cells.
**Item is regulated in the country of origin so an End User Declaration form will be provided via email, upon receipt of the order. Form is required to be completed and returned by the end user. The lead time will be apprx. 8-10 weeks upon receipt of the completed form. Please ensure email address is available on account.
Cayman Chemical Oligomycin A, 579-13-5, 1 mg
An inhibitor of mitochondrial F1FO ATP synthase that induces apoptosis in a variety of cell types (average GI50 = 270 nM); exhibits antifungal, antitumor, and nematocidal activities, but has poor solubility in water and other biocompatible solvents
AdipoGen Latrunculin A,Chemical. CAS: 76343-93-6.
Latrunculin A, AdipoGen Life Sciences. Chemical. CAS: 76343-93-6. Formula: C22H31NO5S. MW: 421.6. Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin). Potent phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in tumor cells. Inhibits tumor cell invasion. Acts via a different mechanism than cytochalasins. 76343-93-6
Sigma Aldrich Fine Chemicals Biosciences Cardiotoxin, Naja pallida | 11061-96-4 | 1MG
Cardiotoxin, Naja pallida | Purity: >=95% (HPLC) | 11061-96-4 | 1MG
Cayman Chemical Convulxin, 37206-04-5, 50 g
A toxin that activates GPVI on platelets and initiates blood clotting.
Cayman Chemical Phalloidin, 17466-45-4, 1 mg
A natural mycotoxin that binds filamentous actin (F-actin) and stabilizes actin fibers; commonly used to stain F-actin in cells when fluorescently labeled
Abraxis Saxitoxin Certified Standard | 20ug/ml | 0.5ml
The Saxitoxins Certified Standard undergoes rigorous analysis for identity and purity, including NMR and UPLC-MS/MS. The intended uses are for the calibration of equipment or a measurement procedure; establishing metrological traceability; method validation; or quality control of a measurement or measurement procedure.
List Biological Laboratories Inc Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae
Since 1978, List Labs products are unsurpassed in quality, consistency, and reliability for the success of your research and development project! Diphtheria toxin, secreted by certain strains of Corynebacterium diphtheriae, catalyzes the ADP-ribosylation of eukaryotic aminoacyl-transferase II (EF-2) using NAD resulting in toxicity toward eukaryotic organisms. It is synthesized and excreted as a proenzyme, of 58 kDa. For its enzymatic activity, the toxin must undergo two covalent alterations. First, mild proteolysis forming “nicked toxin,” which is inactive and consists of two major fragments, A and B, linked by a disulfide bond. Reduction of the nicked toxin with thiols releases the N-terminal A fragment (21 kDa) which is enzymatically active. Diphtheria toxin is produced in the native strain and is offered as "unnicked". Following trypsin treatment and reduction with dithiothreitol, diphtheria toxin from List Labs exhibits high specific activity.
List Biological Laboratories Inc Toxin A from Clostridium difficile, 100 μg
Since 1978, List Labs products are unsurpassed in quality, consistency, and reliability for the success of your research and development projects! Clostridium difficile is the causative agent of antibiotic-associated diarrhea and pseudomembranous colitis. It produces two major exotoxins (Toxin A and Toxin B), which are the prototypes of the family of large clostridial cytotoxins. Clostridium difficile A and B are high molecular weight glucosyltransferases that inhibit members of the Rho family of GTPases. Toxin A, referred to as an enterotoxin, has a molecular weight of 300 kDa and a pl of 5.3. Toxin B, known as a cytotoxin, has a molecular weight of 270 kDa and a pl of 4.1. By inhibition of signal transduction cascades, Toxin A and Toxin B are able to block downstream responses. Only Toxin A has been shown to have a binding site on epithelial cell surface carbohydrates which may be linked to a dramatic reaction seen in rabbit ileum.
List Biological Laboratories Inc Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt, 0.5 mg
Since 1978, List Labs products are unsurpassed in quality, consistency, and reliability for the success of your research and development project! Cholera toxin is an oligomeric protein of 84 kDa size, consisting of a single A subunit surrounded by five B subunits. It is a potent activator of adenylate cyclase and is the pathogenic agent responsible for the symptoms of cholera. Cholera toxin has become a powerful research tool not only in microbiology, but in the fields of physiology, cell biology and biochemistry, as well. Because of the effect on adenylate cyclase, cholera toxin is frequently used for the study of signal transduction mechanisms. The cholera toxin B subunit alone is used for track tracing in neurological research, taking advantage of GM1 ganglioside binding and retrograde transport. Cholera toxin B subunit is isolated from Vibrio cholerae type Inaba 569B and purified from endotoxin.