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Toxins

Toxins

Poisonous agents produced by the metabolic activities of some organisms, and characterized by high molecular weight and antigenicity in certain animals. Includes bacterial, plant, and animal toxins such as botulinum toxin, ricin, and snake venom.

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calcium

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1

Bachem o-Conotoxin GVIA Trifluoroacetate
SDP

o-Conotoxin GVIA Trifluoroacetate, H-Cys-Lys-Ser-Hyp-Gly-Ser-Ser-Cys-Ser-Hyp-Thr-Ser-Tyr-Asn-Cys-Cys-Arg-Ser-Cys-Asn-Hyp-Tyr-Thr-Lys-Arg-Cys-Tyr-NH2, 106375-28-4, C120H182N38O43S6, Mr 3037.39, 0.5mg. o-Conotoxin GVIA from the venom of the fish-hunting cone snail Conus geographus efficiently blocks neuronal calcium channels. This presynaptic inhibition of calcium influx prevents the voltage-activated release of acetylcholine.

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2

List Biological Laboratories Inc Adenylate Cyclase Toxin, Recombinant from B. pertussis, 50 μg
SDP

Since 1978, List Labs products are unsurpassed in quality, consistency, and reliability for the success of your research and development projects! Adenlyate cyclase toxin-hemolysin is an important virulence factor for Bordetella pertussis. It is a large (178 kDa) toxin consisting of an amino-terminal adenylate cyclase and repeat toxin (RTX) moiety. The RTX domain is responsible for target binding, pore-formation, and calcium binding. Adenylate cyclase toxin targets sentinel cells of the host immune system. It penetrates a variety of immune cells and when activated interferes with cell signaling and with the anti-bacterial activity of phagocytes.

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