Drug Standards
Drug Standards
U.S. Pharmacopeia Ibuprofen, 15687-27-1, MFCD00010393, 750mg
Molecular formula C13-H18-O2, Molecular weight 206.28 g/mol, Melting Point 167 - 171.5 °F (75 - 77.5 °C), Synonyms: p-Isobutylhydratropic acid
U.S. Pharmacopeia L-Methionine, 63-68-3, MFCD00063097, 200mg
Molecular formula C5-H11-N-O2-S, Molecular weight 149.21 g/mol, Melting Point 536 - 550.4 °F (280 - 288 °C), Boiling Point 366.8 °F (186 °C)
U.S. Pharmacopeia Ethosuximide, 77-67-8, MFCD00072123, 500mg
Molecular formula C7-H11-N-O2, Molecular weight 141.17 g/mol, Melting point/freezing point 116.6 - 125.6 °F (47 - 52 °C), Synonyms: 2-Ethyl-2-Methylsuccinimide
TARGETMOL CHEMICALS INC 11-oxo-mogroside V 20MG
11-oxo-mogroside V (11-oxo Mogroside V) is a sweet tasting cucurbitane glycoside derivative of mogroside V. It has antioxidant effects against both O2- and OH- and prevents OH-induced DNA damage. Purity 99.82%
TARGETMOL CHEMICALS INC ISRADIPINE 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Isradipine (PN 200-110) is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vascular smooth muscle thereby dilating coronary arteries and peripheral arterioles. This increases oxygen delivery due to an increased blood flow and reduces oxygen requirements due to decreasing in total peripheral resistance. purity: 99%
Cayman Chemical OxIbendazole 250mg
An essential ceramide for prevention of epidermal water loss found in the outer epidermis of mammals consecutive regio- and stereospecific oxygenation of the linoleate portion by 12(R)-LO and eLOX3 is essential for the maintenance of the epidermal barrier to prevent water loss has been found in intact and desquamated human stratum corneum as well as porcine epidermis
AdipoGen Metformin . HCl (1 g)
Metformin . HCl (1 g), Adipogen Life Sciences. Chemical. CAS: 1115-70-4. Formula: C4H11N5 . HCl. MW: 129.2 . 36.5. . AMPK activator. Useful agent for immunometabolism research. Reported to stimulate AMP-activated protein kinase (AMPK), leading to the reduction in acetyl-CoA carboxylase (ACC) activity and induction of fatty acid oxidation. Mitochondrial electron transport chin complex I inhibitor, reducing mitochondrial reactive oxygen species (ROS). Antidiabetic and anti-hyperglycemic agent that reduces blood glucose levels, improves insulin sensitivity and decreases insulin resistance. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated in part by activation of the LKB1-AMPK pathway. Used as weight-loss agent in obesity and as insulin sensitizer in nonalcoholic fatty liver disease (NAFLD). Leptin sensitizer to mediate the weight-loss effect in the brain. Targets brown adipose tissue (BAT) in vivo and reduces oxygen consumption.
Selleck Chemical LLC Temozolomide 10mM/1mL 85622-93-1 CCRG81045, NSC 362856,TMZ
Temozolomide (CCRG81045, NSC 362856, TMZ) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Temozolomide 100mg 85622-93-1 CCRG81045, NSC 362856,TMZ
Temozolomide (CCRG81045, NSC 362856, TMZ) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Apexbio Technology LLC Pitavastatin Calcium, 147526-32-7, MFCD00916490, 25 mg
MF: C50H46CaF2N2O8, MW: 880.98, Solubility: 34.85mg/mL in DMSO. Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.
AdipoGen Menadione, 58-27-5, MFCD00001681, 1 g
MF: C11H8O2, MW: 172.2, ≥98%, Appearance: Off-white to yellow solid. Synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2 (menaquinone) after alkylation in vivo. The 1,4-naphthoquinone (NQ) moiety can form redox isomers by accepting one or two electrons respectively. The quinone redox cycling ability leads to the generation of reactive oxygen species (ROS) as well as arylation reactions. Anticancer compound. Apoptosis inducer in various cultured cells including leukemia through several modes of action.
Apexbio Technology LLC Pitavastatin Calcium, 147526-32-7, MFCD00916490, 10 mg
MF: C50H46CaF2N2O8, MW: 880.98, Solubility: 34.85mg/mL in DMSO. Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.