Hydroxybenzoic Acid Derivatives
Hydroxybenzoic Acid Derivatives
Raclopride, Tocris Bioscience™
CAS: 84225-95-6 Molecular Formula: C15H20Cl2N2O3 Molecular Weight (g/mol): 347.236 InChI Key: WAOQONBSWFLFPE-VIFPVBQESA-N Synonym: raclopride,s-3,5-dichloro-n-1-ethylpyrrolidin-2-yl methyl-2-hydroxy-6-methoxybenzamide,3h raclopride,3h-raclopride,unii-430k3soz7g,chembl8809,raclopridum latin,racloprida spanish,raclopride inn:ban,dsstox_cid_25687 PubChem CID: 3033769 IUPAC Name: 3,5-dichloro-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxybenzamide SMILES: CCN1CCCC1CNC(=O)C2=C(C(=CC(=C2OC)Cl)Cl)O
Cayman Chemical 2 3-DIhydroxybenzoIc AcId 5g
An active metabolite of ropinirole increases extracellular acidification rates in CHO cells expressing human dopamine D2 D3 and D4 receptors (EC50s 0 63 0 063 and 1 23 UM respectively) a potential impurity found in commercial preparations of ropinirole
TARGETMOL CHEMICALS INC Nolomirole HCl 1MG
Also available in 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Nolomirole HCl (CHF 1035) is a novel selective dopamine agonist with oral activity and inhibitory effects on norepinephrine release, which can be used to study mild chronic heart failure. Purity 99.12%
TARGETMOL CHEMICALS INC TETRAHYDROBERBERINE 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber has a micromolar affinity for dopamine D(2) receptors. purity: 99%
TARGETMOL CHEMICALS INC 4-Hydroxyderricin 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. 4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50 3.43 uM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine beta-hydroxylase (DBH) activity and possesses antidepressant activity. Purity 98%
TARGETMOL CHEMICALS INC SB-277011 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0 6.0 5.0 and <5.2 for D3 receptor D2 receptor 5-HT1D and 5-HT1B respectively. purity: 98%
TARGETMOL CHEMICALS INC Acetylcorynoline 20MG
Also available in 1 mL and bulk. Please contact Fisher for quotes. 1. Acetylcorynoline (O-Acetylcorynoline) has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3. Acetylcorynoline is potential as a possible antiparkinsonian drug. (1) Significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; (2) Prevents alpha-synuclein aggregation; (3) Restores food-sensing behavior, and dopamine levels; (4) Prolongs life-span in 6-hydroxydopamine-treated N2 strain. 4. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes. Purity 99.45%
TARGETMOL CHEMICALS INC EMEDASTINE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Emedastine (LY188695) is a second generation selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors thus blocking its downstream activity. As a result this agent interferes with mediator release from mast cells either by inhibiting calcium ion influx across mast cell/basophil plasma membrane or by inhibiting intracellular calcium ion release within the cells. In addition emedastine may also inhibit the late-phase allergic reaction mediated through leukotrienes or prostaglandins or by producing an anti-platelet activating factor effect. Upon ocular administration emedastine causes a dose-dependent inhibition of histamine-stimulated vascular permeability in the conjunctiva. Emedastine does not affect adrenergic dopamine or serotonin receptors. purity: 97%