Synonym: 4-(2-aminoethyl)-benzene-sulfonyl fluoride, aebsf, aminoethyl-benzene-sulfonyl fluoride, 4-2-, proteinase k inhibitor. Pefabloc SC is used to inhibit the detrimental effects of proteases during preparative protein purification. Due to its low toxicity toward eukaryotic cells, it may be applied in the production of recombinant proteins, during fermentation of transformed cells, where proteolytic digestion may decrease the yield of the desired product.