Bioactive Small Molecules
Bioactive Small Molecules
Tocris Bioscience™ CU-T12-9
Potent TLR1/2 agonist
Tocris Bioscience™ CU-76
Selective inhibitor of cyclic GMP-AMP synthase (cGAS)
Tocris Bioscience™ CU CPT 9a
Potent TLR8 inhibitor
Tocris Bioscience™ Disulfide biotin azide
Azide-activated biotinylation reagent; labels alkyne moieties via copper-catalyzed click chemistry
Tocris Bioscience™ THPTA
Click chemistry auxiliary reagent; accelerating ligand for copper-catalyzed azide-alkyne cycloaddition reaction
Tocris Bioscience™ TBTA
Click chemistry auxiliary reagent; stabilizing ligand for copper-catalyzed azide-alkyne cycloaddition reaction
Tocris Bioscience™ Biotin-PEG3-Azide
Biotin with PEG linker and reactive click handle
Tocris Bioscience™ DBCO PEG4 Biotin
Biotinylation reagent for labeling azide-containing biomolecules via Cu(I)-free click chemistry
Tocris Bioscience™ DBCO-NHS
Amine reactive and azide reactive building block
Tocris Bioscience™ Janelia Fluor™ 635, Tetrazine
Red dye (Reactive group: tetrazine). Application: confocal microscopy, super resolution microscopy including dSTORM & STED. Suitable for live cell imaging
Tocris Bioscience™ VH 032 amide-PEG3-BCN
Functionalized VHL building block for copper-free click chemistry
Tocris Bioscience™ Ac4ManNAz
Azide-containing monosaccharide building block; used as glycoprotein, glycolipid and glycoRNA probe
Cayman Chemical ANTIBODY CU-CPT9a 1mg
A cyclotetrapeptide fungal metabolite active against C pyogenes S aureus P aeruginosa and K pneumonia bacteria (MICs 25 13 6 and 21 g/cm3 respectively) active against C albicans M audouinii A niger and Ganoderma fungi (MICs 13 6 25 and 6 g/cm3 respectively)
Cayman Chemical ANTIBODY CU-CPT9a 25mg
A polyketide with diverse biological activities inhibits growth of HeLa S3 SK-MEL-2 PC3 A549 and EBC-1 cells (GI50s 7 4-62 nM) is cytostatic against HUVECs (IC50 26 nM) inhibits VEGF-induced invasion and tube formation of serum-starved HUVECs inhibits HIF-1a mRNA splicing and reduces HIF-1a protein levels in HepG2 cells grown under hypoxic conditions at 0 05 M inhibits splicing of p27Kip mRNA in HeLa cells increases LDL receptor promoter-driven transcription in a cell-based reporter assay at 0 1 and 1 M
Invivogen CU-CPT9a, 10 mg
CU-CPT9a is a potent and selective inhibitor of Toll-like receptor 8 (TLR8).
