Pyrazines
Pyrazines
TARGETMOL CHEMICALS INC RANOLAZINE 200MG
Also available in 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ranolazine (RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel used to treat chronic angina. It affects the sodium-dependent calcium channels during myocardial ischemia in rabbits by altering the intracellular sodium level. purity: 98%
STEMCELL Technologies Tacrine Hydrochloride
L-type calcium channel inhibitor; Inhibits acetylcholinesterase and butyrylcholinesterase - 5 G
TARGETMOL CHEMICALS INC SESAMODIL 5MG
Also available in 50 mg 100 mg and bulk. Please contact Fisher for quotes. Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension. purity: 99%
TARGETMOL CHEMICALS INC LEVOSEMOTIADIL 5MG
Also available in 50 mg 100 mg and bulk. Please contact Fisher for quotes. Levosemotiadil（SA 3212） is a novel calcium antagonist and a very potent inhibitor of low-density lipoprotein oxidation.Levosemotiadil may be used to prevent lethal cardiac arrhythmias. purity: 99%
TARGETMOL CHEMICALS INC PD0176078 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PD0176078 () is a newly blocker of N-type Calcium channel. purity: 97%
TARGETMOL CHEMICALS INC CRONIDIPINE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Cronidipine (LF 20254) a calcium channel antagonist is used potentially for the treatment of hypertension and myocardia ischemia. purity: 99%
TARGETMOL CHEMICALS INC SURFACTIN 10MG
Also available in 1 mg 5 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations such as calcium across lipid bilayer membranes with anti-bacterial anti-fungal antimycoplasma and hemolytic effects.
TARGETMOL CHEMICALS INC RO 67-7476 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM. purity: 99%
TARGETMOL CHEMICALS INC DALTROBAN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells. purity: 99%
TARGETMOL CHEMICALS INC VATANIDIPINE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Vatanidipine (AE0047) is a novel dihydropyridine (DHP)-type calcium channel blocker with slow-onset pharmacological actions.A slow-onset and long-lasting hypotensive action was observed in various experimental hypertensive models. purity: 100%
TARGETMOL CHEMICALS INC PRANIDIPINE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pranidipine (OPC-13340) is a novel long-acting 14-dihydropyridine calcium channel blocker. It prolongs acetylcholine-induced relaxation in presence of endothelium as well as nitroglycerin-induced relaxation in absence of endothelium. It also has antihypertensive activity. purity: 99%
TARGETMOL CHEMICALS INC PHYSALIN F 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.It is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBMC decreasing the spontaneous proliferation and cytokine production caused by Human T-lymphotropic virus type 1 (HTLV-1) infectionpurity: 99%
TARGETMOL CHEMICALS INC TALNIFLUMATE 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome. purity: 99%
TARGETMOL CHEMICALS INC G36 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. G36 is a cell-permeable non-steroidal antagonist of GPER. G36 inhibits activation by either 17(beta)-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 nM respectively). G36 has no detectable binding activity to either ER(alpha) or ER(beta). G36 blocks the activation of PI3K or calcium mobilization triggered by estrogen through GPER and it suppresses ERK activation by estrogen or G-1 but not by EGF. G-36 can be used in combination with GPER-selective agonists like G-1 to distinguish the roles of GPER from those of ER(alpha) and ER(beta) in complex biological systems. purity: 99%
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