Signal Transduction Reagents and Kits
Signal Transduction Reagents and Kits
Thermo Scientific Chemicals Ionomycin Calcium Salt, 99%
CAS: 56092-82-1 Molecular Formula: C41H70CaO9 Molecular Weight (g/mol): 747.08 InChI Key: RULWQOBWZOQCOY-SQNLDGQHSA-M IUPAC Name: calcium (4R,6S,8S,12R,14R,16E,18R,19R,20S,21S)-19,21-dihydroxy-22-[(2S,2'R,5S,5'S)-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl-[2,2'-bioxolan]-5-yl]-4,6,8,12,14,18,20-heptamethyl-9,11-dioxodocos-16-en-10-idoate SMILES: [Ca++].C[C@H](CCC([O-])=O)C[C@H](C)C[C@H](C)C(=O)[CH-]C(=O)[C@H](C)C[C@H](C)C\C=C\[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@](C)(O1)[C@H]1CC[C@](C)(O1)[C@@H](C)O
Thermo Scientific Chemicals Vinpocetine, 98%
CAS: 42971-09-5 Molecular Formula: C22H26N2O2 Synonym: Eburnamenine-14-carboxylic acid ethyl ester
Thermo Scientific Chemicals Calmidazolium Chloride
CAS: 57265-65-3 Molecular Formula: C31H24Cl7N2O Molecular Weight (g/mol): 688.70 InChI Key: LBFGPQFQXRJXDI-UHFFFAOYNA-N IUPAC Name: 1-[bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-2,3-dihydro-1H-imidazole hydrochloridyl SMILES: [Cl].ClC1=CC=C(C=C1)C(N1CN(CC(OCC2=CC=C(Cl)C=C2Cl)C2=CC=C(Cl)C=C2Cl)C=C1)C1=CC=C(Cl)C=C1
Thermo Scientific Chemicals SKF-96365 hydrochloride, 99+%
CAS: 130495-35-1 Molecular Formula: C22H27ClN2O3 Synonym: 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]imidazole
Thermo Scientific Chemicals Calpeptin, ≥98%
CAS: 117591-20-5 Molecular Formula: C20H30N2O4 Synonym: N-Benzyloxycarbonyl-L-leucyl-norleucinal; Z-Leu-norleucinal
Thermo Scientific Chemicals TRAM 34
CAS: 289905-88-0 Molecular Formula: C22H17ClN2 Molecular Weight (g/mol): 344.84 InChI Key: KBFUQFVFYYBHBT-UHFFFAOYSA-N Synonym: 1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole IUPAC Name: 1-[(2-chlorophenyl)diphenylmethyl]-1H-pyrazole SMILES: ClC1=CC=CC=C1C(N1C=CC=N1)(C1=CC=CC=C1)C1=CC=CC=C1
Promega Kinase Selectivity Profiling System: CAMK-1 + ADP-Glo™ Assay
Easy-to-use kits for performing kinase selectivity profiling that rely on the ADP-Glo™ Kinase Assay technology. Each system includes kinase and substrate pairs in an easy-to-use 8-tube strip format optimized for fast and simple kinase profiling reactions.
Promega Kinase Selectivity Profiling System: CAMK-2 + ADP-Glo™ Assay
Easy-to-use kits for performing kinase selectivity profiling that rely on the ADP-Glo™ Kinase Assay technology. Each system includes kinase and substrate pairs in an easy-to-use 8-tube strip format optimized for fast and simple kinase profiling reactions.
Aat Bioquest Cal-590™ AM | 5x50ug
Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Rhod-2 is most commonly used among the red fluorescent calcium indicators. However, Rhod-2 AM is only moderately fluorescent in live cells upon esterase hydrolysis, and has very small cellular calcium responses. Cal-590™ has been developed to improve Rhod-2 cell loading and calcium response while maintaining the spectral wavelength of Rhod-2, making it compatible with TRITC/Cy3 filter set. In CHO and HEK cells Cal-590™ AM has cellular calcium response that is much more sensitive than Rhod-2 AM.
Aat Bioquest Calbryte 520 AM (10x50 ug)
The intracellular calcium flux assay is a widely used method in monitoring signal transduction pathways and high throughput screening of G proteinquotcoupled receptors GPCRs and calcium channel targets. This catalog is for 10x50 ug.
Aat Bioquest CALBRYTE-520 ASSAY KIT 1 PLATE
Calbryte-520 Probenecid-Free and Wash-Free Calcium Assay Kit 1 plate
Aat Bioquest Calbryte™ 520 AM | 1mg
Calbryte™ 520, AM is a novel fluorescent and cell-permeable indicator for the measurement of intracellular calcium. Like other dye AM esters, Calbryte™ 520 AM is non-fluorescent and non-activatable. Once Calbryte™ 520 AM enters the cell, it is readily hydrolyzed by intracellular esterase where it becomes activated and responsive to calcium. The activated indicator is now a polar molecule that is incapable of freely diffusing through the cell membrane, essentially trapping it inside the cell. Upon binding calcium ions, Calbryte™ 520 produces a bright fluorescence signal with extremely high signal/background ratio. It has the identical excitation and emission wavelength as Fluo-4, thus the same Fluo-4 assay settings can be readily applied to Calbryte™ 520-based calcium assays.
Aat Bioquest Calbryte™ 520 AM | 2x50ug
The intracellular calcium flux assay is a widely used method in monitoring signal transduction pathways and high throughput screening of G protein"coupled receptors (GPCRs) and calcium channel targets. Followed by Fluo-3 being introduced in 1989, Fluo-4, Fluo-8 and Cal-520 were later developed with improved signal/background ratio, and became the widely used Ca2+ indicators for confocal microscopy, flow cytometry and high throughput screening applications. However, there are still a few severe problems with Fluo-4. For example, as for Fluo-3, in all most all the intracellular calcium assays with Fluo-4 AM, probenecid is required to prevent the cell-loaded Fluo-4 from leaking out of cells. The use of probenecid with Fluo-4-based calcium assays compromises the assay results since probenecid is well-documented to have a variety of complicated cellular effects. Calbryte™ 520, AM is a novel fluorescent and cell-permeable indicator for the measurement of intracellular calcium.
Enzo Life Sciences L-cis-Diltiazem HCl (5mg). CAS: 42399-54-2
Blocks cyclic nucleotide-gated calcium channels. Purity: ≥98%. Solubility: Soluble in water (>10mg/ml). Long Term Storage: Ambient.
Enzo Life Sciences MMP-1 Colorimetric Assay Buffer (20ml)
Formulation: Liquid. In 50 mM HEPES, 10 mM calcium chloride, 0.05% Brij-35, 1 mM DTNB, pH 7.5. Long Term Storage: -20°C.
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