Search results for "Enzo Life Sciences"
Enzo Life Sciences PARP-1 (human), (recombinant) (high purity) (20 µg)
Synonyms: Poly(ADP-ribose) polymerase 1. UniProt ID: P09874. Source: Produced in Sf9 insect cells. Produced in a baculovirus expression system. Purification: Affinity purified. Formulation: Liquid. In 100mM TRIS-HCl, pH 7.5, containing 14mM β-mercaptoethanol, 0.5mM EDTA, 0.5mM PMSF and 10% glycerol.
Enzo Life Sciences DIPPMPO (50 mg)
Spin trapping reagent. Beside DEPMPO (Prod. No. ALX-430-093), most efficient spin trap for the in vitro and in vivo detection of O-, N-, S-, and C-centered free radicals. Has a longer life-time than DMPO (Prod. No. ALX-430-090). More lipophilic (Kp=2.1) than DEPMPO. Synonyms: 5-(Diisopropoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide. Formula: C11H22NO4P. MW: 263.3.
Enzo Life Sciences BAFF monoclonal antibody (Buffy-2) (100 µg)
Synonyms: B cell-activating factor, BLyS, TALL-1, THANK, zTNF4, TNFSF 13B/20, CD257. Clone: Buffy-2. Host: Rat. Isotype: IgM. Immunogen: Recombinant human soluble BAFF (aa 83-285) (Prod. No. ALX-522-025). UniProt ID: Q9Y275. Source: Purified from ascites. Species reactivity: Human. Applications: Flow Cytometry, IHC (FS), IHC (PS), WB. Purification: Purified by IgM purification HP column. Formulation: Liquid. In PBS containing 0.02% sodium azide.
Enzo Life Sciences Cathepsin F (human), (recombinant) (5 µg)
Highly active. MW: ~39kDa. UniProt ID: Q9UBX1. Source: Produced in insect cells (secreted) as untagged proenzyme; activated during purification. Produced in a baculovirus expression system. Purification: Purified by multi-step chromatography. Formulation: Liquid. In 20mM NaOAc, pH 5.0, containing 2.5mM EDTA, 250mM sodium chloride and 20mM L-cysteine.
Enzo Life Sciences Tetanus toxoid (100 µg)
Inactivation with formaldehyde leads to non-toxic form of tetanus toxin. Produced from tetanus toxin by inactivation with formaldehyde. The resulting toxoid is essentially non-toxic. Synonyms: Formaldehyde inactivated tetanus toxin. MW: ~150kDa. UniProt ID: P04958. Formulation: Lyophilized.
Enzo Life Sciences mTOR (human FRB Domain) polyclonal antibody (1 Vial)
Synonyms: mTOR (human FKBP12-rapamycin-binding domain). Host: Rabbit. Immunogen: Recombinant human mTOR (FKBP12-rapamycin-binding (FRB) domain). UniProt ID: P42345. Species reactivity: Human. Applications: ICC, WB, ChIP. Formulation: Lyophilized from neat serum containing sodium azide.
Enzo Life Sciences CFSE (25 mg) CAS: 150347-59-4
Amine dye. Non-toxic cell permeable fluorescent dye that reacts with amine compounds. Readily accumulates inside viable cells. Hardly leaks from cells when covalently attached to intracellular proteins. Hydrolyzed CFSE emits fluorescence (Ex(max): 495nm; Em(max): 519nm). Therefore, CFSE is utilized for the long-term observation of cell activities by fluorescent microscopy as well as for viable cell detection. Synonyms: 5(6)-(N-Succinimidyloxycarbonyl)-3',6',0,0'-diacetylfluorescein, 5(6)-Carboxyfluorescein diacetate, N-succinimidyl ester-. Formula: C29H19NO11. MW: 557.5.
Enzo Life Sciences Proteasome 20S β5i subunit monoclonal antibody (LMP7-1) (100 µl)
Synonyms: Proteasome subunit β type-8, LMP7, RING10 protein, Macropain subunit C13. Clone: LMP7-1. Host: Mouse. Isotype: IgG1. Immunogen: Recombinant human proteasome subunit β5i. UniProt ID: P28062. Source: Purified from ascites. Species reactivity: Human, Rat. Applications: IHC, WB. Purification: Protein G affinity purified. Formulation: Liquid. In PBS, pH 7.4, containing 10mM sodium azide.
Enzo Life Sciences Phospholipase D (Streptomyces chromofuscus) (25 kU)
Synonyms: PLD, Phosphatidylcholine phosphatidohydrolase. MW: ~60kDa (~40kDa heterodimer). UniProt ID: Q8KRU5. Source: Isolated from Streptomyces chromofuscus. Purification: Purified by multi-step chromatography. Formulation: Liquid. In 100mM TRIS-HCl, pH 8.0, containing 10% v/v glycerol, 0.1% w/v Triton X-100.
Enzo Life Sciences CATHEPSIN L (HUMAN LIVER), (PURIFIED) [25 µg]
CATHEPSIN L (HUMAN LIVER), (PURIFIED) [25 µg]
Enzo Life Sciences p300 (catalytic domain) (human), (recombinant) (100 µg)
Synonyms: E1A binding protein p300, Histone acetyltransferase p300. MW: 45.1 kDa. UniProt ID: Q09472. Source: Produced in E. coli. Catalytic domain (aa 1284-1673) of human p300. Purification: Partially purified by single-step affinity chromatography and gel filtration. Formulation: Liquid. In 50mM TRIS/HCl, pH 8.0, containing 0.1mM EDTA, 10% glycerol.
Enzo Life Sciences CHO host cell protein ELISA kit (96 wells)
Sensitive (10 ng/ml) ELISA for the quantitative determination of host cell protein contamination in bulk products expressed in Chinese Hamster Ovary (CHO) expression systems. The CHO host cell protein ELISA kit is a complete, colorimetric, immunometric immunoassay kit for the quantitative determination of Chinese Hamster Ovary (CHO) host cell protein contamination with results in 3 hours Sensitivity: 10 ng/ml (range 3-810 ng/ml). Assay Time: 3 hours. Applications: ELISA, Colorimetric detection.
Enzo Life Sciences Gambogic acid (5mg). CAS: 2752-65-0
Gambogic Acid is a natural product isolated from Garcinia Hurburyi. It induces apoptosis in several tumor cell lines including T47D breast cancer cells and MGC-803 human gastric carcinoma cells but not in normal cells. Apoptosis induction proceeds via upregulation of bax and inhibition of bcl-2 expression.The target of gambogic acid has been identified as the transferrin receptor. Purity: ≥95% (TLC). Solubility: Soluble in DMSO (25 mg/ml) or ethanol (25 mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences Necrostatin-1 (100mg). CAS: 4311-88-0
Necrostatin-1 inhibits necroptosis, a non-apoptotic cell death pathway. Inhibits the loss of mitochondrial membrane potential in TNFα-treated Jurkat cells (EC50=490 nM). Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. It displays a pronounced protective effect in a mouse model of ischemic brain injury and inhibits myocardial cell death. Inhibits RIP1 kinase the key upstream kinase involved in the activation of necroptosis (EC50=180nM). Alternative name: Methylthiohydantoin-DL-tryptophan. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (20mg/ml) or 100% ethanol (5mg/ml). Long Term Storage: Ambient.
Enzo Life Sciences Timosaponin AIII (5mg). CAS: 41059-79-4
Induces autophagy in HeLa cells followed by apoptotic cell death (IC50=10μM). This cellular response has been found to be mediated via inhibition of mTORC1 and induction of ER stress (IC50 for BT474 cells=2.5µM and MDAMB231 cells=6µM). The pro-apoptotic response is selective for tumor cells over normal cells but autophagy is induced in both. Purity: ≥96% (HPLC). Solubility: Soluble in DMSO (20 mg/ml). Long Term Storage: -20°C.