Hydroxybenzoic Acid Derivatives
Hydroxybenzoic Acid Derivatives
ML 218 hydrochloride, Tocris Bioscience™
CAS: 2319922-08-0 Molecular Formula: C19H27Cl3N2O Molecular Weight (g/mol): 405.788 InChI Key: IDCVEUISZZKMKJ-ZXVFAPHLSA-N Synonym: ml 218 hydrochloride,3,5-dichloro-n-1?,5?,6-exo,6?-3-3,3-dimethylbutyl-3-azabicyclo 3.1.0 hex-6-yl methyl-benzamide hydrochloride PubChem CID: 90488946 IUPAC Name: 3,5-dichloro-N-[[(1S,5R)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]benzamide;hydrochloride SMILES: CC(C)(C)CCN1CC2C(C1)C2CNC(=O)C3=CC(=CC(=C3)Cl)Cl.Cl
Sigma Organic Chemistry L-Threonic acid hemicalcUM s5G
L-THREONIC ACID CALCIUM SALT 97% [ 5G [ 380644-5G [97% [ 70753-61-6 [ MFCD00077882[C8H14CaO10
TARGETMOL CHEMICALS INC ETRIPAMIL 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Etripamil (MSP-2017) displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells. Etripamil is an antagonist of short-acting L-type calcium-channel. It has a rapid onset of action designed for intranasal administration. It is also used to treat Paroxysmal Supraventricular Tachycardia. purity: 99%
Sigma Organic Chemistry CalcUM trifluoromethansulf 50G
Calcium trifluoromethanesulfonate 99 9% [ PuritY 99 9% [ Mol Wt 338 22 [ 55120-75-7 [ MFCD00143911 [ 50G
Cayman Chemical 7-BromoheptnoIc AcId 5g
An L-type calcium channel blocker inhibits calcium-induced contraction of rabbit ear artery (pA2 9 4) induces relaxation of calcium-induced contractions in isolated rat colon and bladder and guinea pig trachea (IC50s 6 7 6 and 7 8 nM respectively) induces negative inotropy in isolated guinea pig ventricular strips (IC50 110 nM) reduces mean blood pressure in spontaneously hypertensive rats (ED25 0 35 mg/kg) and in renal hypertensive dogs (ED25 0 22 mg/kg) inhibits copper-induced oxidation of isolated human LDL at 1 and 5 UM reduces the extension of aortic atheromatous lesions and decreases renal injury in ApoE-/- mice in a model of Western diet-induced atherosclerosis
Sigma Aldrich Fine Chemicals Biosciences 3355 Tetramethylbenzidine25G
3 3AE 5 5AE-Tetramethylbenzidine is a peroxidase sensitive dye. It is a better alternative to syringaldazine for the determination of chlorine in water due to its product stability and no interference from calcium and magnesium ions.
TARGETMOL CHEMICALS INC SB-237376 HCl 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. SB-237376 HCl (SB-237376 hydrochloride) is a calcium and potassium channel antagonist used in the treatment of cardiac arrhythmias. Purity 99.49%
TARGETMOL CHEMICALS INC SB-423562 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis. purity: 98%
TARGETMOL CHEMICALS INC Caldaret HCl 1MG
Also available in 2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Caldaret HCl is an intracellular Ca2+ modulator that regulates calcium homeostasis at the sarcoplasmic reticulum and cell membrane, and can be used to study acute myocardial infarction and heart failure. Purity 99.06%
TARGETMOL CHEMICALS INC AM966 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AM966 a excellent affinity specific oral LPA1(IC50=17 nM) antagonist suppresses LPA-stimulated intracellular calcium release. purity: 98%
TARGETMOL CHEMICALS INC EMEDASTINE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Emedastine (LY188695) is a second generation selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors thus blocking its downstream activity. As a result this agent interferes with mediator release from mast cells either by inhibiting calcium ion influx across mast cell/basophil plasma membrane or by inhibiting intracellular calcium ion release within the cells. In addition emedastine may also inhibit the late-phase allergic reaction mediated through leukotrienes or prostaglandins or by producing an anti-platelet activating factor effect. Upon ocular administration emedastine causes a dose-dependent inhibition of histamine-stimulated vascular permeability in the conjunctiva. Emedastine does not affect adrenergic dopamine or serotonin receptors. purity: 97%
TARGETMOL CHEMICALS INC CHIKUSETSUSAPONIN IVA 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Chikusetsusaponin IVa (Calenduloside F) is a novel AMPK activator can induce insulin secretion from (beta)TC3 cells via GPR4 mediated calcium and PKC pathways may be developed into a new potential for therapeutic agent used in T2DM patients. purity: 99%
TARGETMOL CHEMICALS INC Taurodeoxycholic acid 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Taurodeoxycholic acid (Taurodeoxychloic acid) is a bile acid taurine conjugate of deoxycholic acid, a human metabolite that stabilizes mitochondrial membranes and reduces the formation of free radicals.Taurodeoxycholic acid inhibits apoptosis by blocking calcium-mediated apoptotic pathways and by activation of caspase-12. Taurodeoxycholic acid has neuroprotective activity and has been used to study 3-nitropropionic acid-induced or stabilized hereditary Huntington's chorea (HD). Purity 99.22%
AdipoGen Paxilline
Chemical. CAS 57186-25-1. Formula C27H33NO4. MW 435.6. Isolated from Penicillium sp. Tremorgenic. Potent, selective and reversible inhibitor of high-conductance calcium-activated potassium BKCa channels. Reversible inhibitor of inositol 1,4,5-trisphosphate receptor InsP3. Sarco/endoplasmic reticulum Ca2 ATPase SERCA inhibitor. Liver X receptor LXRalpha and LXRbeta NR1H3 and NR1H2 agonist in biochemical and in vitro cell-based assays. Anticonvulsant. Apoptosis enhancer. Can sensitize various glioma cells to TRAIL-mediated apoptosis. Shown to protect neuronal cells against glutamate-induced cell death.
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