Benzoxazines
Benzoxazines
AdipoGen Lucigenin
Chemical. CAS 2315-97-1. Formula C28H22N4O6. MW 510.5. Synthetic. Chemiluminescent probe for the detection of peroxides in biological systems. Reagent used for the generation of chemiluminescence in the presence of a reductant and oxygen It is employed in numerous chemiluminescent assays. Lucigenin is specific for superoxide anion radical.
AdipoGen Lucigenin
Chemical. CAS 2315-97-1. Formula C28H22N4O6. MW 510.5. Synthetic. Chemiluminescent probe for the detection of peroxides in biological systems. Reagent used for the generation of chemiluminescence in the presence of a reductant and oxygen It is employed in numerous chemiluminescent assays. Lucigenin is specific for superoxide anion radical.
AdipoGen Palmarumycin C3
Chemical. CAS 159934-11-9. Formula C20H12O6. MW 348.3. Isolated from Sphaeropsidales sp. Rasfarnesyltransferase inhibitor. Antifungal, antibacterial and herbicidal. Structurally unique natural products. The basic structure of palmarumycin C1 can be modified by a number of hydroxylation, oxygenation, dehydrogenation and chlorination steps. Antioxidant
AdipoGen Palmarumycin C3
Chemical. CAS 159934-11-9. Formula C20H12O6. MW 348.3. Isolated from Sphaeropsidales sp. Rasfarnesyltransferase inhibitor. Antifungal, antibacterial and herbicidal. Structurally unique natural products. The basic structure of palmarumycin C1 can be modified by a number of hydroxylation, oxygenation, dehydrogenation and chlorination steps. Antioxidant
TARGETMOL CHEMICALS INC VISOMITIN 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Visomitin (SKQ1) is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS). purity: 98%
AdipoGen DCFDA
Chemical. CAS 2044-85-1. Formula C24H14Cl2O7. MW 485.27. Synthetic. A cell-permeable fluorogenic dye useful for the detection of reactive oxygen species ROS and nitric oxide NO and for the determination of the degree of overall oxidative stress. The fluorescence of DCFDA indicates oxidation by hydrogen peroxide, peroxynitrite or hydroxyl radical. Superoxide anions can also contribute to DCFDA oxidation albeit at a lesser degree. It measures hydroxyl, peroxyl and other reactive oxygen species ROS activity within the cell. After diffusion in to the cell, DCFDA is deacetylated by cellular esterases to a non-fluorescent compound, which is later oxidized by ROS into the highly fluorescent 2’,7’-dichlorofluorescein DCF. Spectral data lambdaex=504nm, lambdaem=524nm in 0.1 M Tris pH 8.0 esterase.
TARGETMOL CHEMICALS INC Research Chemical 500mg
Also available in 25 mg, 50 mg, 100 mg, 200 mg, 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 2',7'-Dichlorofluorescein diacetate (Diacetyldichlorofluorescein), a cell-permeable fluorogenic probe, is useful for the detection of nitric oxide (NO) and reactive oxygen species (ROS) and for the determination of the degree of overall oxidative stress. purity: 99%
Cayman Chemical 7-EthoxyresorufIn 1mg
A minor bioactive component of ginger with anti-inflammatory and anticancer properties induces apoptosis in cancer cells through the production of reactive oxygen species and the activation of caspase impairs tubulin polymerization downregulates NF-KB signaling inhibits the expression of inflammatory mediators suppresses Toll-like receptor signaling and enhances antioxidant defense mechanisms by inducing Nrf2/ARE-mediated gene expression
TARGETMOL CHEMICALS INC AKOS037652256 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. AKOS037652256 can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity such as lysosomal accumulation disorders muscular dystrophy common age-related neurodegenerative diseases oxidative stress or reactive oxygen species (ROS)-related diseases and ageing. purity: 98%
TARGETMOL CHEMICALS INC GSK2795039 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50 6 in different cell-free assays). purity: 98%
AdipoGen DAR-4M Solution
Chemical. CAS 339527-79-6. Formula C25H26N4O3. MW 430.51. Synthetic Photo-stable fluorescent probe Ex ~560nm Em 575nm for the detection of nitric oxide NO in presence of oxygen, resulting in a triazolo-rhodamine analog DAR-4M T that exhibits about 840-fold greater fluorescence quantum efficiency. Suitable probe for monitoring RNS production, but not NO alone. Stable in a pH range of 4-12. Detection limit ~10nM.
AdipoGen DAR-4M
Chemical. CAS 339527-79-6. Formula C25H26N4O3. MW 430.51. Synthetic Photo-stable fluorescent probe Ex ~560nm Em 575nm for the detection of nitric oxide NO in presence of oxygen, resulting in a triazolo-rhodamine analog DAR-4M T that exhibits about 840-fold greater fluorescence quantum efficiency. Suitable probe for monitoring RNS production, but not NO alone. Stable in a pH range of 4-12. Detection limit ~10nM.
AdipoGen DAR-4M
Chemical. CAS 339527-79-6. Formula C25H26N4O3. MW 430.51. Synthetic Photo-stable fluorescent probe Ex ~560nm Em 575nm for the detection of nitric oxide NO in presence of oxygen, resulting in a triazolo-rhodamine analog DAR-4M T that exhibits about 840-fold greater fluorescence quantum efficiency. Suitable probe for monitoring RNS production, but not NO alone. Stable in a pH range of 4-12. Detection limit ~10nM.
TARGETMOL CHEMICALS INC SFI003 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SFI003 is a novel SRSF3 inhibitor that exerts anticancer activity against colorectal cancer by modulating the SRSF3 / DHCR24 / ROS axis and driving apoptosis in CRC cells through the SRSF3 / DHCR24 / reactive oxygen species (ROS) axis. purity: 99%
TARGETMOL CHEMICALS INC NM-3 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. NM-3 is an orally available anti-angiogenic inhibitor with anti-tumour activity.NM-3 is used as a radiation modulator in vitro and in vivo.NM-3 inhibits vascular endothelial growth factor (VEGF) thereby inhibiting the proliferation of endothelial cells. This inhibits the proliferation of endothelial cells. NM-3 is associated with a mechanism of apoptosis induction by reactive oxygen species. purity: 98%
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